Schreiner Andrew M, Yang Grace C H
Department of Pathology and Laboratory Medicine, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York 10065, USA.
Diagn Cytopathol. 2009 Mar;37(3):213-6. doi: 10.1002/dc.21041.
Medullary thyroid carcinoma typically presents as dyscohesive plasmacytoid, spindled, or polygonal cells on fine-needle aspiration smears. We recently encountered a case of sporadic medullary thyroid carcinoma that presented as a hypercellular aspirate composed of cohesive aggregates of rectangle-shaped cells. The case was mistakenly reported as a hypercellular follicular neoplasm on cytology. Subsequent thyroidectomy revealed medullary carcinoma. We draw attention to this distinctive rectangular cell type as an additional morphology for medullary thyroid carcinoma.
甲状腺髓样癌在细针穿刺涂片上通常表现为细胞间缺乏黏附性的浆细胞样、梭形或多边形细胞。我们最近遇到一例散发性甲状腺髓样癌,其细针穿刺物细胞丰富,由矩形细胞的黏附性聚集体组成。该病例在细胞学检查中被误诊为细胞丰富的滤泡性肿瘤。随后的甲状腺切除术显示为髓样癌。我们提请注意这种独特的矩形细胞类型,它是甲状腺髓样癌的另一种形态。