Int J Cardiol. 2010 Sep 3;143(3):e51-3. doi: 10.1016/j.ijcard.2008.12.044. Epub 2009 Jan 20.
Takotsubo cardiomyopathy (TTC) is a new clinical entity characterised by acute but rapidly reversible left ventricular systolic dysfunction. This case report demonstrates the unique finding of a complete normalization of left ventricular function in a patient with TTC in only 36 h documented by cardiac magnetic resonance imaging. To our best knowledge, this is the most rapid complete recovery of left ventricular apical ballooning reported, yet. Medical management of our patient included optimized antihypertensive therapy with intravenous administration of the α-1-adrenergic blocker urapidil and the ß-blocker bisoprolol in highest recommended doses. Although optimal management of TTC has not been established, α- and β-blockade may be beneficial for rapid recovery of TTC and may be protective against the recurrence of stress-related left ventricular dysfunction due to acute and sudden catecholamine excess.
心尖球囊样综合征（TTC）是一种新的临床实体，其特征为急性但迅速可逆的左心室收缩功能障碍。本病例报告显示了通过心脏磁共振成像在 36 小时内记录到 TTC 患者的左心室功能完全正常的独特发现。据我们所知，这是迄今为止报告的左心室心尖球囊样综合征最快的完全恢复。我们患者的药物治疗包括优化的降压治疗，静脉给予 α-1 肾上腺素能阻滞剂乌拉地尔和最高推荐剂量的β受体阻滞剂比索洛尔。虽然 TTC 的最佳治疗尚未确定，但 α-和 β-阻滞剂可能有益于 TTC 的快速恢复，并可能防止由于急性和突然儿茶酚胺过多引起的应激相关左心室功能障碍的复发。
