Zouves C, Erenus M, Gomel V
Department of Obstetrics and Gynaecology, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Fertil Steril. 1991 Oct;56(4):691-5. doi: 10.1016/s0015-0282(16)54601-9.
To assess predisposing factors to tubal pregnancy after in vitro fertilization-embryo transfer (IVF-ET).
Retrospective analysis of 891 ET cycles.
University-based IVF program.
PATIENTS, PARTICIPANTS: All ET cycles performed in the study period were included; the indication for IVF was tubal factor in 640 (72%) and other (nontubal) factors in 251 (28%) cycles.
None.
Observing a higher than expected number of tubal pregnancies in our program; we examined subgroups to determine those at highest risk.
Tubal pregnancies comprised 12% of clinical pregnancies in the tubal factor group but only 2.6% in the cycles nontubal factor group (P less than 0.05). Of 640 ET cycles in the tubal factor group, 359 were performed in patients who had prior tubal reconstructive surgery; tubal pregnancies comprised 15.6% of the clinical gestations in this subgroup. In the remainder of the tubal factor group (no prior tubal surgery), 281 ET cycles yielded a tubal pregnancy rate of only 5.5% (P less than 0.05).
Women with prior reconstructive surgery for distal tubal disease are at highest risk of developing tubal pregnancy after IVF.
评估体外受精-胚胎移植（IVF-ET）后输卵管妊娠的 predisposing 因素。
对891个胚胎移植周期进行回顾性分析。
大学附属体外受精项目。
患者、参与者：纳入研究期间进行的所有胚胎移植周期；IVF的指征为输卵管因素的有640个周期（72%），其他（非输卵管）因素的有251个周期（28%）。
无。
观察我们项目中输卵管妊娠数量高于预期；我们检查亚组以确定风险最高的人群。
输卵管因素组中输卵管妊娠占临床妊娠的12%，而非输卵管因素组的周期中仅占2.6%（P<0.05）。在输卵管因素组的640个胚胎移植周期中，359个是在曾接受输卵管重建手术的患者中进行的；该亚组中输卵管妊娠占临床妊娠的15.6%。在输卵管因素组的其余患者（未进行过输卵管手术）中，281个胚胎移植周期的输卵管妊娠率仅为5.5%（P<0.05）。
既往因远端输卵管疾病接受重建手术的女性在IVF后发生输卵管妊娠的风险最高。
