Tatsis G, Orphanidou D, Douratsos D, Mellissinos C, Pantelakis D, Pipini E, Jordanoglou J
Pulmonary Department, Sotiria Hospital, Athens University, Greece.
J Int Med Res. 1991 Jul-Aug;19(4):326-9. doi: 10.1177/030006059101900405.
The effect of hydrocortisone on plasma theophylline concentrations was evaluated in 20 patients suffering from chronic bronchitis or stable bronchial asthma. Choline theophyllinate (400 mg) was orally administered every 12 h for 8 days and blood samples were taken every 2 h during the day for the measurement of theophylline concentrations. Intravenous bolus injections of 500 or 1000 mg hydrocortisone on day 5 or day 7, respectively, did not significantly alter plasma theophylline concentrations.
在20例患有慢性支气管炎或稳定期支气管哮喘的患者中评估了氢化可的松对血浆茶碱浓度的影响。每12小时口服400mg胆茶碱，持续8天，白天每2小时采集血样以测定茶碱浓度。分别在第5天或第7天静脉推注500mg或1000mg氢化可的松，并未显著改变血浆茶碱浓度。
