Endeshaw Yohannes
Department of Medicine, Emory University School of Medicine, Atlanta, GA 30329, USA.
J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):142-8. doi: 10.1093/gerona/gln009. Epub 2009 Jan 20.
Nocturia is a common and bothersome problem with multifactorial etiology. This study examines clinical factors that are associated with nocturia among community-dwelling older adults.
A questionnaire-based survey was conducted among a convenience sample of community-dwelling older adults. Nocturia was defined as waking up to urinate two or more times per night for 3 or more days per week. Associations between nocturia status and sleep disturbance, daytime sleepiness, disease burden, and history of falls were determined.
Questionnaires were mailed out to 433 participants, and returned questionnaires from 247 individuals (58%) individuals were adequate for analysis. There were 144 women (57%) and 103 men (42%), with mean +/- standard deviation age of 75.1 +/- 6.9 and 76.6 +/- 5.6 years for women and men, respectively. A total of 137 participants (55%) endorsed nocturia, and 57 participants (23%) endorsed nocturia and difficulty going back to sleep. Participants who endorsed nocturia and difficulty going back to sleep were more likely to report poor sleep quality, daytime sleepiness, increased disease burden, one or more falls, and symptoms related to primary sleep disorders.
The clinical characteristics of study participants with nocturia and difficulty going back to sleep were different from those with nocturia and no difficulty going back to sleep, suggesting that these two conditions may have different etiological factors and clinical consequences. These findings would have important implications in both clinical and research-related activities aimed at the management of nocturia in older adults.
夜尿症是一个常见且令人困扰的问题,其病因是多因素的。本研究调查了社区居住的老年人中与夜尿症相关的临床因素。
对社区居住的老年人进行了一项基于问卷的调查。夜尿症定义为每周有3天或更多天每晚醒来排尿两次或更多次。确定了夜尿症状态与睡眠障碍、日间嗜睡、疾病负担和跌倒史之间的关联。
向433名参与者邮寄了问卷,247名个体(58%)返回的问卷足以进行分析。其中有144名女性(57%)和103名男性(42%),女性和男性的平均年龄分别为75.1±6.9岁和76.6±5.6岁。共有137名参与者(55%)认可夜尿症,57名参与者(23%)认可夜尿症且难以重新入睡。认可夜尿症且难以重新入睡的参与者更有可能报告睡眠质量差、日间嗜睡、疾病负担增加、一次或多次跌倒以及与原发性睡眠障碍相关的症状。
有夜尿症且难以重新入睡的研究参与者的临床特征与有夜尿症但不难重新入睡的参与者不同,这表明这两种情况可能有不同的病因和临床后果。这些发现对于旨在管理老年人夜尿症的临床和研究相关活动都具有重要意义。