Lautenbacher S, Strian F
Clinical Department, Max Planck Institute for Psychiatry, Munich, Germany.
Funct Neurol. 1991 Apr-Jun;6(2):129-35.
Age differences in the thresholds for heat pain, warmth and cold were studied in 64 healthy persons from 17 to 63 years of age (32 women, 32 men). The stimuli were applied to the thenar and the dorsum pedis with a contact thermode. The thresholds increased significantly with age in all modalities on the foot, but not on the hand. Furthermore, the quotients of the individual foot and hand thresholds revealed a significant relative increase in all thresholds on the foot. The length of the afferent pathways seems to influence the degree of age-related changes both in heat pain perception and in thermal sensitivity, resulting in a distal-proximal pattern of age-dependent decline.
对64名年龄在17至63岁之间的健康人(32名女性,32名男性)进行了热痛、温热和冷觉阈值的年龄差异研究。使用接触式热刺激器将刺激施加于鱼际和足背。足部所有感觉模式的阈值均随年龄显著增加,但手部没有。此外,个体足部和手部阈值的商数显示足部所有阈值有显著的相对增加。传入通路的长度似乎影响热痛觉和热敏感性方面与年龄相关的变化程度,导致年龄依赖性下降呈现从远端到近端的模式。