具有网状内皮组织增殖症病毒和水疱性口炎病毒混合衣壳的水疱性口炎病毒假型。
Pseudotypes of vesicular stomatitis virus with the mixed coat of reticuloendotheliosis virus and vesicular stomatitis virus.
作者信息
Kang C Y, Lambright P
出版信息
J Virol. 1977 Mar;21(3):1252-5. doi: 10.1128/JVI.21.3.1252-1255.1977.
Abstract
Vesicular stomatitis virus (VSV) forms pseudotypes with envelope components of reticuloendotheliosis virus (REV). The VSV pseudotype possesses the limited host range and antigenic properties of REV. Approximately 70% of the VSV, Indiana serotype, and 45% of VSV, New Jersey serotype, produced from the REV strain T-transformed chicken bone marrow cells contain mixed envelope components of both VSV and REV. VSV pseudotypes with mixed envelope antigens can be neutralized with excess amounts of either anti-VSV antiserum or anti-REV antiserum.
摘要
水泡性口炎病毒（VSV）与网状内皮组织增殖症病毒（REV）的包膜成分形成假型。VSV假型具有REV有限的宿主范围和抗原特性。由REV菌株T转化的鸡骨髓细胞产生的约70%的印第安纳血清型VSV和45%的新泽西血清型VSV含有VSV和REV的混合包膜成分。具有混合包膜抗原的VSV假型可以用过量的抗VSV抗血清或抗REV抗血清中和。
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