Razavi M E, Abotoraby R B, Kakhki R D, Ghanavati S Z, Layegh P, Taghavi M, Rajabian M T
Department of Ophthalmology, Khatam-Al-Anbia Eye Hospital, Medical University of Mashad, Mashad, Islamic Republic of Iran.
East Mediterr Health J. 2008 Jul-Aug;14(4):841-9.
This study evaluated the prevalence and severity of ophthalmic manifestations in all Graves disease patients (n = 68) presenting to endocrine clinics at Mashad University of Medical Sciences between December 2002 and September 2005. The mean age of patients was 38.0 (SD 14.0) years, range 15 to 71 years. The most common complaints were foreign body sensation (54.0%) and puffy eyelids (48.4%). The most common apparent abnormality was lid retraction in 64.2% of patients (bilateral in 95.3% of cases). The patients had a mean modified Werner's NO SPECS classification score of 3.00 (SD 1.46). The score was significantly higher in males than females [3.58 (SD 1.44) versus 2.63 (SD 1.35)] and was positively correlated with age.
本研究评估了2002年12月至2005年9月期间在马什哈德医科大学内分泌诊所就诊的所有格雷夫斯病患者（n = 68）眼部表现的患病率和严重程度。患者的平均年龄为38.0（标准差14.0）岁，年龄范围为15至71岁。最常见的症状是异物感（54.0%）和眼睑肿胀（48.4%）。最常见的明显异常是64.2%的患者出现眼睑退缩（95.3%的病例为双侧）。患者改良的维尔纳NO SPECS分类评分平均为3.00（标准差1.46）。该评分在男性中显著高于女性[3.58（标准差1.44）对2.63（标准差1.35）]，且与年龄呈正相关。
