Eshraghi Bahram, Nikdel Mojgan, Abbasi Maryam
Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Private Practice, Rasht, Iran.
J Curr Ophthalmol. 2022 Apr 16;34(1):106-111. doi: 10.4103/joco.joco_223_21. eCollection 2022 Jan-Mar.
To focus on clinical manifestations and epidemiology of thyroid eye disease (TED) in Central Iran's population.
In this retrospective case study, we analyzed all patients with TED who were referred to our oculoplastic clinic from 2015 to 2019. The patients' epidemiological characteristics and clinical presentation were compared between different thyroid disease groups and genders.
Overall, 383 patients (155 male; 40.5% and 228 female; 59.5%) were included. The mean age was 39.55 years (standard deviation ± 13.45, range 10-72). Most patients (89%) were hyperthyroid with the highest duration of ocular involvement among all categories (25.6 months). The most common signs on ophthalmic examinations were proptosis (80.4%), followed by eyelid retraction (72.3.0%). TED was classified as mild in 24.5%, moderate to severe in 67.6%, and sight-threatening in 7.9%. Thirty patients (7.8%) had active TED.
This series with a relatively more significant number of TED cases in Central Iran found similar epidemiological and clinical characteristics of TED compared to other studies from Iran. Most of our patients were hyperthyroid, with more females compared to males. Proptosis and eyelid retraction were the most common manifestations. Most TED patients were classified as moderate to severe.
关注伊朗中部人群甲状腺眼病（TED）的临床表现和流行病学情况。
在这项回顾性病例研究中，我们分析了2015年至2019年转诊至我们眼部整形门诊的所有TED患者。比较了不同甲状腺疾病组和不同性别患者的流行病学特征及临床表现。
总共纳入了383例患者（男性155例，占40.5%；女性228例，占59.5%）。平均年龄为39.55岁（标准差±13.45，范围10 - 72岁）。大多数患者（89%）患有甲状腺功能亢进，在所有类别中眼部受累时间最长（25.6个月）。眼科检查中最常见的体征是眼球突出（80.4%），其次是眼睑退缩（72.3%）。TED被分类为轻度的占24.5%，中度至重度的占67.6%，威胁视力的占7.9%。30例患者（7.8%）患有活动性TED。
该系列研究纳入了伊朗中部相对较多的TED病例，发现与伊朗其他研究相比，TED的流行病学和临床特征相似。我们的大多数患者患有甲状腺功能亢进，女性多于男性。眼球突出和眼睑退缩是最常见的表现。大多数TED患者被分类为中度至重度。
