Rossano Joseph W, Jefferson Larry S, Smith E O'Brian, Ward Mark A, Mott Antonio R
Department of Pediatrics, Lillie Frank Abercrombie Section of Pediatric Cardiology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX 77030, USA.
J Pediatr. 2009 May;154(5):672-6. doi: 10.1016/j.jpeds.2008.11.051. Epub 2009 Jan 23.
To test the hypothesis that pediatric residents would have shorter time to attempted defibrillation using automated external defibrillators (AEDs) compared with manual defibrillators (MDs).
A prospective, randomized, controlled trial of AEDs versus MDs was performed. Pediatric residents responded to a simulated in-hospital ventricular fibrillation cardiac arrest and were randomized to using either an AED or MD. The primary end point was time to attempted defibrillation.
Sixty residents, 21 (35%) interns, were randomized to 2 groups (AED = 30, MD = 30). Residents randomized to the AED group had a significantly shorter time to attempted defibrillation [median, 60 seconds (interquartile range, 53 to 71 seconds)] compared with those randomized to the MD group [median, 103 seconds (interquartile range, 68 to 288 seconds)] (P < .001). All residents in the AED group attempted defibrillation at <5 minutes compared with 23 (77%) in the MD group (P = .01).
AEDs improve the time to attempted defibrillation by pediatric residents in simulated cardiac arrests. Further studies are needed to help determine the role of AEDs in pediatric in-hospital cardiac arrests.
检验以下假设,即与手动除颤器(MD)相比,儿科住院医师使用自动体外除颤器(AED)尝试除颤的时间会更短。
对AED与MD进行了一项前瞻性、随机、对照试验。儿科住院医师对模拟的院内室颤心脏骤停做出反应,并被随机分配使用AED或MD。主要终点是尝试除颤的时间。
60名住院医师,其中21名(35%)为实习医师,被随机分为两组(AED组 = 30人,MD组 = 30人)。与随机分配到MD组的住院医师相比,随机分配到AED组的住院医师尝试除颤的时间明显更短[中位数为60秒(四分位间距为53至71秒)],而MD组为[中位数为103秒(四分位间距为68至288秒)](P <.001)。AED组的所有住院医师均在<5分钟时尝试除颤,而MD组为23名(77%)(P = .01)。
在模拟心脏骤停中,AED可缩短儿科住院医师尝试除颤的时间。需要进一步研究以帮助确定AED在儿科院内心脏骤停中的作用。