Folke Fredrik, Lippert Freddy Knudsen, Nielsen Søren Loumann, Gislason Gunnar Hilmar, Hansen Morten Lock, Schramm Tina Ken, Sørensen Rikke, Fosbøl Emil Loldrup, Andersen Søren Skøtt, Rasmussen Søren, Køber Lars, Torp-Pedersen Christian
Research Fellow, Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark, Niels Andersens Vej 65, 2900 Hellerup, Denmark.
Circulation. 2009 Aug 11;120(6):510-7. doi: 10.1161/CIRCULATIONAHA.108.843755. Epub 2009 Jul 27.
Public-access defibrillation with automated external defibrillators (AEDs) is being implemented in many countries worldwide with considerable financial implications. The potential benefit and economic consequences of focused or unfocused AED deployment are unknown.
All cardiac arrests in public in Copenhagen, Denmark, from 1994 through 2005 were geographically located, as were 104 public AEDs placed by local initiatives. In accordance with European Resuscitation Council and American Heart Association (AHA) guidelines, areas with a high incidence of cardiac arrests were defined as those with 1 cardiac arrest every 2 or 5 years, respectively. There were 1274 cardiac arrests in public locations. According to the European Resuscitation Council or AHA guidelines, AEDs needed to be deployed in 1.2% and 10.6% of the city area, providing coverage for 19.5% (n=249) and 66.8% (n=851) of all cardiac arrests, respectively. The excessive cost of such AED deployments was estimated to be $33 100 or $41 000 per additional quality-adjusted life year, whereas unguided AED placement covering the entire city had an estimated cost of $108 700 per quality-adjusted life year. Areas with major train stations (1.8 arrests every 5 years per area), large public squares, and pedestrianized areas (0.6 arrests every 5 years per area) were main predictors of frequent cardiac arrests.
To achieve wide AED coverage, AEDs need to be more widely distributed than recommended by the European Resuscitation Council guidelines but consistent with the American Heart Association guidelines. Strategic placement of AEDs is pivotal for public-access defibrillation, whereas with unguided initiatives, AEDs are likely to be placed inappropriately.
在全球许多国家,自动体外除颤器(AED)的公众可及性除颤正在实施,这涉及大量财政支出。聚焦式或非聚焦式AED部署的潜在益处和经济后果尚不清楚。
对丹麦哥本哈根1994年至2005年期间所有公共场所发生的心脏骤停事件进行地理定位,同时对当地倡议放置的104台公共AED也进行了地理定位。根据欧洲复苏委员会和美国心脏协会(AHA)的指南,心脏骤停高发地区分别定义为每2年或5年发生1次心脏骤停的地区。公共场所共发生1274次心脏骤停事件。根据欧洲复苏委员会或AHA指南,分别需要在城市面积的1.2%和10.6%部署AED,分别可为所有心脏骤停事件的19.5%(n = 249)和66.8%(n = 851)提供覆盖。这种AED部署的额外成本估计为每增加一个质量调整生命年33,100美元或41,000美元,而覆盖整个城市的无指导AED放置估计成本为每质量调整生命年108,700美元。设有大型火车站(每个区域每5年1.8次骤停)、大型公共广场和步行区(每个区域每5年0.6次骤停)的地区是心脏骤停频发的主要预测因素。
为实现广泛的AED覆盖,AED的分布范围需要比欧洲复苏委员会指南建议的更广泛,但要与美国心脏协会指南一致。AED的战略放置对于公众可及性除颤至关重要,而在无指导的倡议下,AED可能放置不当。