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穿孔性胃溃疡的根治性手术还是保守性手术?——一个尚未解决的问题。

Definitive or conservative surgery for perforated gastric ulcer?--An unresolved problem.

作者信息

Sarath Chandra Sistla, Kumar S Siva

机构信息

Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605006, India.

出版信息

Int J Surg. 2009 Apr;7(2):136-9. doi: 10.1016/j.ijsu.2008.12.037. Epub 2008 Dec 25.

Abstract

BACKGROUND

Gastric ulcer perforation has not been the focus of many studies. In addition there is a need to analyze the results of gastric perforation separately and not along with duodenal perforations, to identify the factors influencing the outcome and to develop strategies for its management.

MATERIALS AND METHODS

Retrospective analysis of 54 patients presenting with gastric perforation.

RESULTS

Mean age of the patients was 44.5 years with male preponderance. Morbidity following Closure of the perforation, acid reduction surgery and resection was not significantly different. Overall mortality was 16.6% with highest mortality 24.1% following simple closure. Mortality following simple closure and definitive surgery was not significantly different. Univariate analysis revealed preoperative shock, associated medical illness and surgical delay to be significant factors for mortality whereas on multivariate analysis, preoperative shock was the only independent predictor of mortality. Mortality increased with increasing Boey score but the association between the type of surgery and probability of survival was not statistically significant.

CONCLUSION

Boey risk score is useful in predicting the outcome of surgical treatment for gastric perforation. Definitive surgery is not associated with greater morbidity or mortality compared to simple closure.

摘要

背景

胃溃疡穿孔尚未成为众多研究的焦点。此外,有必要单独分析胃穿孔的结果,而不是与十二指肠穿孔一起分析,以确定影响预后的因素并制定其管理策略。

材料与方法

对54例胃穿孔患者进行回顾性分析。

结果

患者的平均年龄为44.5岁,男性居多。穿孔闭合、抑酸手术和切除术的发病率无显著差异。总体死亡率为16.6%,单纯闭合术后死亡率最高,为24.1%。单纯闭合术和确定性手术后的死亡率无显著差异。单因素分析显示术前休克、相关内科疾病和手术延迟是死亡率的重要因素,而多因素分析显示术前休克是死亡率的唯一独立预测因素。死亡率随Boey评分增加而升高,但手术类型与生存概率之间的关联无统计学意义。

结论

Boey风险评分有助于预测胃穿孔手术治疗的结果。与单纯闭合术相比,确定性手术的发病率和死亡率并未更高。

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