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一项关于在专科心力衰竭护士护理基础上增加家庭锻炼的随机试验:针对充血性心力衰竭患者的伯明翰康复吸收最大化研究(BRUM-CHF研究)

A randomized trial of the addition of home-based exercise to specialist heart failure nurse care: the Birmingham Rehabilitation Uptake Maximisation study for patients with Congestive Heart Failure (BRUM-CHF) study.

作者信息

Jolly Kate, Taylor Rod S, Lip Gregory Y H, Davies Mick, Davis Russell, Mant Jonathan, Singh Sally, Greenfield Sheila, Ingram Jackie, Stubley Jane, Bryan Stirling, Stevens Andrew

机构信息

Department of Public Health and Epidemiology, University of Birmingham, Public Health Building, and University Department of Medicine, City Hospital, Birmingham B15 2TT, UK.

出版信息

Eur J Heart Fail. 2009 Feb;11(2):205-13. doi: 10.1093/eurjhf/hfn029.

Abstract

AIMS

Supervised exercise can benefit selected patients with heart failure, however the effectiveness of home-based exercise remains uncertain. We aimed to assess the effectiveness of a home-based exercise programme in addition to specialist heart failure nurse care.

METHODS AND RESULTS

This was a randomized controlled trial of a home-based walking and resistance exercise programme plus specialist nurse care (n=84) compared with specialist nurse care alone (n=85) in a heart failure population in the West Midlands, UK.

PRIMARY OUTCOME

Minnesota Living with Heart Failure Questionnaire (MLwHFQ) at 6 and 12 months.

SECONDARY OUTCOMES

composite of death, hospital admission with heart failure or myocardial infarction; psychological well-being; generic quality of life (EQ-5D); exercise capacity. There was no statistically significant difference between groups in the MLwHFQ at 6 month (mean, 95% CI) (-2.53, -7.87 to 2.80) and 12 month (-0.55, -5.87 to 4.76) follow-up or secondary outcomes with the exception of a higher EQ-5D score (0.11, 0.04 to 0.18) at 6 months and lower Hospital Anxiety and Depression Scale score (-1.07, -2.00 to -0.14) at 12 months, in favour of the exercise group. At 6 months, the control group showed deterioration in physical activity, exercise capacity, and generic quality of life.

CONCLUSION

Home-based exercise training programmes may not be appropriate for community-based heart failure patients.

摘要

目的

有监督的运动对部分心力衰竭患者有益,但居家运动的效果仍不确定。我们旨在评估除了由专业心力衰竭护士护理外,居家运动计划的效果。

方法与结果

这是一项随机对照试验,在英国西米德兰兹郡的心力衰竭患者中,将居家步行和抗阻运动计划加专业护士护理(n = 84)与单纯专业护士护理(n = 85)进行比较。

主要结局

6个月和12个月时的明尼苏达心力衰竭生活问卷(MLwHFQ)。

次要结局

死亡、因心力衰竭或心肌梗死住院的综合情况;心理健康;一般生活质量(EQ - 5D);运动能力。在6个月(均值,95%置信区间)(-2.53,-7.87至2.80)和12个月(-0.55,-5.87至4.76)随访时,两组在MLwHFQ或次要结局方面无统计学显著差异,但运动组在6个月时EQ - 5D评分较高(0.11,0.04至0.18),在12个月时医院焦虑抑郁量表评分较低(-1.07,-2.00至-0.14)。在6个月时,对照组在身体活动、运动能力和一般生活质量方面出现恶化。

结论

居家运动训练计划可能不适用于社区心力衰竭患者。

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