Ahman M, Alexandersson R, Ekholm U, Bergström B, Dahlqvist M, Ulfvarson U
Department of Occupational Medicine, Huddinge Hospital, Sweden.
Int Arch Occup Environ Health. 1991;63(3):175-80. doi: 10.1007/BF00381565.
A total of 39 moulders and coremakers exposed to furan resin sand and 27 unexposed local controls were examined by lung-function tests before and after a work shift. In all, 28 of the subjects exposed to furan resin sand and the control group were evaluated by dynamic spirometry and nitrogen washout. The remaining 11 subjects exposed to furan resin sand were studied using both static and dynamic spirometry and the CO single-breath technique. The time-weighted average exposure to furfuryl alcohol was about 7 mg/m3, with peak values exceeding the present Swedish short-term exposure limit (40 mg/m3). The exposure to respirable dust and formaldehyde as time-weighted over the shift was less than 2 mg/m3 and 0.4 mg/m3, respectively, in all groups. During the work shift studied, the 28 exposed subjects had more complaints of airway symptoms than did the controls, showing an average decrease of 0.21 in forced vital capacity but no fall in any other lung-function variable. The remaining 11 exposed subjects demonstrated a post-shift decrease in total lung capacity. The results indicate an acute restrictiveness induced by exposure to furan resin sand, but the underlying mechanism is unclear. Chronic impairment of lung function was not observed.
共有39名接触呋喃树脂砂的造型工和制芯工以及27名未接触的当地对照人员在一个工作班次前后接受了肺功能测试。总共对28名接触呋喃树脂砂的受试者和对照组进行了动态肺量测定和氮洗脱评估。其余11名接触呋喃树脂砂的受试者采用静态和动态肺量测定以及单次呼吸一氧化碳技术进行研究。糠醇的时间加权平均暴露量约为7毫克/立方米，峰值超过了目前瑞典的短期暴露限值（40毫克/立方米）。所有组中班次时间加权的可吸入粉尘和甲醛暴露量分别低于2毫克/立方米和0.4毫克/立方米。在所研究的工作班次期间，28名接触的受试者气道症状主诉比对照组更多，用力肺活量平均下降了0.21，但其他肺功能变量未下降。其余11名接触的受试者在班次结束后肺总量下降。结果表明接触呋喃树脂砂会引起急性限制性通气障碍，但其潜在机制尚不清楚。未观察到肺功能的慢性损害。
