Bardel Annika, Wallander Mari-Ann, Wedel Hans, Svärdsudd Kurt
Uppsala University, Department of Public Health and Caring Sciences, Family Medicine and Clinical Epidemiology Section, Uppsala, Sweden.
BMC Public Health. 2009 Jan 26;9:37. doi: 10.1186/1471-2458-9-37.
Symptom prevalence is generally believed to increase with age. The aim of this study was to evaluate the age specific prevalence of 30 general symptoms among Swedish middle-aged women.
A cross-sectional postal questionnaire study in seven Swedish counties in a random sample of 4,200 women 35-64 years old, with 2,991 responders. Thirty general symptoms included in the Complaint Score subscale of the Gothenburg Quality of Life Instrument were used.
Four groups of age specific prevalence patterns were identified after adjustment for the influence of educational level, perceived health and mood, body mass index, smoking habits, use of hormone replacement therapy, and use of other symptom relieving therapy. Only five symptoms (insomnia, leg pain, joint pain, eye problems and impaired hearing) increased significantly with age. Eleven symptoms (general fatigue, headache, irritability, melancholy, backache, exhaustion, feels cold, cries easily, abdominal pain, dizziness, and nausea) decreased significantly with age. Two symptoms (sweating and impaired concentration) had a biphasic course with a significant increase followed by a significant decrease. The remaining twelve symptoms (difficulty in relaxing, restlessness, overweight, coughing, breathlessness, diarrhoea, chest pain, constipation, nervousness, poor appetite, weight loss, and difficulty in urinating) had stable prevalence with age.
Symptoms did not necessarily increase with age instead symptoms related to stress-tension-depression decreased.
一般认为症状患病率会随着年龄增长而增加。本研究旨在评估瑞典中年女性中30种常见症状的年龄特异性患病率。
在瑞典的七个县进行了一项横断面邮政问卷调查研究,随机抽取4200名35 - 64岁的女性,有2991人回复。使用了哥德堡生活质量量表投诉评分子量表中包含的30种常见症状。
在对教育水平、感知健康和情绪、体重指数、吸烟习惯、激素替代疗法的使用以及其他症状缓解疗法的使用等影响因素进行调整后,确定了四组年龄特异性患病率模式。只有五种症状(失眠、腿痛、关节痛、眼部问题和听力受损)随年龄显著增加。十一种症状(全身疲劳、头痛、易怒、忧郁、背痛、疲惫、感觉寒冷、容易哭泣、腹痛、头晕和恶心)随年龄显著减少。两种症状(出汗和注意力不集中)呈双相过程,先显著增加,随后显著减少。其余十二种症状(难以放松、坐立不安、超重、咳嗽、呼吸急促、腹泻、胸痛、便秘、紧张、食欲不振、体重减轻和排尿困难)的患病率随年龄稳定。
症状不一定随年龄增加,相反,与压力 - 紧张 - 抑郁相关的症状减少。