Moravvej Hamideh, Razavi Gita Meshkat, Farshchian Mehdi, Malekzadeh Reza
Skin Research Center, Shahid Beheshti Medical University, Shohada-e Tajrish Hospital, Tehran, Iran.
Indian J Dermatol Venereol Leprol. 2008 Nov-Dec;74(6):607-10. doi: 10.4103/0378-6323.45102.
Cutaneous manifestations of inflammatory bowel disease are relatively common, although they vary widely.
The aim of this study was to determine the prevalence of cutaneous manifestations in inflammatory bowel disease according to their location, age, gender, activity, and type of underlying disease in an Iranian population during a 10-year period.
The medical records of 404 inpatients with inflammatory bowel disease were extracted retrospectively to detect cutaneous manifestations.
In this study, the prevalence of cutaneous manifestations was 5.9%. These manifestations were higher in Crohn's disease (7.29%) than in ulcerative colitis (4.07%), and more frequent in females (52%) than in males (48%). Aphthous stomatitis was observed more frequently in Crohn's disease; however, pyoderma gangrenosum was seen more often in ulcerative colitis. Erythema nodosum was diagnosed only in female patients with Crohn's disease. Manifestations secondary to nutritional deficiency or associated conditions including psoriasis and other autoimmune disorders were less frequent.
Aphthous stomatitis, pyoderma gangrenosum, and erythema nodosum were the most common skin disorders related to inflammatory bowel disease (IBD), which mainly occurred in women.
炎症性肠病的皮肤表现相对常见，尽管差异很大。
本研究的目的是确定在10年期间，伊朗人群中炎症性肠病皮肤表现的患病率，根据其部位、年龄、性别、活动情况以及潜在疾病类型进行分析。
回顾性提取404例炎症性肠病住院患者的病历，以检测皮肤表现。
在本研究中，皮肤表现的患病率为5.9%。这些表现在克罗恩病（7.29%）中高于溃疡性结肠炎（4.07%），女性（52%）比男性（48%）更常见。口疮性口炎在克罗恩病中更常见；然而，坏疽性脓皮病在溃疡性结肠炎中更常见。结节性红斑仅在患有克罗恩病的女性患者中被诊断出。营养缺乏或相关病症（包括银屑病和其他自身免疫性疾病）继发的表现较少见。
口疮性口炎、坏疽性脓皮病和结节性红斑是与炎症性肠病（IBD）相关的最常见皮肤疾病，主要发生在女性身上。
