Virdi Sarvjit Kaur, Kanwar Amrinder Jit Singh
Department of Dermatology, PGIMER, Sector 12, Chandigarh-160 012, India.
Indian J Dermatol Venereol Leprol. 2009 Jan-Feb;75(1):56-9. doi: 10.4103/0378-6323.45222.
Generalized morphea is a disease characterized by wide-spread sclerosis of the skin. A 39-year-old man presented with history of multiple pigmented and bound-down plaques on the body along with mucosal involvement. Dermatological examination showed multiple indurated and sclerosed plaques with follicular plugging in few of them and gross thickened eroded and glazed tongue. The constellation of these findings with histopathological correlation led us to diagnosis of this spectrum of cutaneous involvement. The coexistence of localized morphea with lichen sclerosis et atrophicus has been reported earlier but existence of these entities with submucosal fibrosis in a same patient is documented here and is the first of its kind.
泛发性硬斑病是一种以皮肤广泛硬化为特征的疾病。一名39岁男性患者,身上有多处色素沉着且边界固定的斑块,并伴有黏膜受累。皮肤科检查发现多处硬结和硬化斑块,部分斑块有毛囊堵塞,舌头明显增厚、糜烂且表面光滑。这些发现与组织病理学结果相结合,使我们诊断出这种皮肤受累情况。此前已有局限性硬斑病与硬化萎缩性苔藓共存的报道,但同一患者同时存在这些病变及黏膜下纤维化的情况在此有记录,且属首例。