Hu J F, Liu Y Y, Yu Y K, Zhao T Z, Liu S D, Wang Q Q
Department of Epidemiology, Harbin Medical College, Heilogjiang, China.
Int J Epidemiol. 1991 Jun;20(2):362-7. doi: 10.1093/ije/20.2.362.
A case-control study was carried out in Harbin city to assess the role of diet in the aetiology of colorectal cancer. A total of 336 incident cases of histologically confirmed colorectal cancer (111 colon cancer and 225 rectal cancer) and an equal number of controls with other non-neoplastic diseases were interviewed in hospital wards. Data concerning the average frequency of consumption and amount consumed of single food items were obtained by a dietary history questionnaire. Odds ratios and their confidence limits were computed. Multiple regression for risk status was also used. Vegetables, particularly green vegetables, chives and celery, have a strong protective effect against colorectal cancer. Reduced consumption of meat, eggs, bean products and grain was associated with increasing risk for cancer of the rectum. Alcohol intake was found to be an important risk factor for developing colon cancer and male rectal cancer.
在哈尔滨市开展了一项病例对照研究,以评估饮食在结直肠癌病因学中的作用。在医院病房对总共336例经组织学确诊的结直肠癌患者(111例结肠癌和225例直肠癌)以及同等数量患有其他非肿瘤性疾病的对照者进行了访谈。通过饮食史问卷获取了关于单一食物项目平均食用频率和食用量的数据。计算了比值比及其置信区间。还使用了风险状态的多元回归分析。蔬菜,尤其是绿色蔬菜、韭菜和芹菜,对结直肠癌有很强的保护作用。肉类、蛋类、豆制品和谷物的摄入量减少与直肠癌风险增加有关。发现饮酒是发生结肠癌和男性直肠癌的重要风险因素。