Luo Cheng-wang, Chen Hua-xin
National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2008 Oct;29(10):1017-9.
To study the epidemiological characteristics and vaccination strategy of hemorrhagic fever with renal syndrome (HFRS) in China, from 1998 to 2007.
National data on the prevalence of HFRS during 1998 to 2007 were collected and analyzed. Spatial, time and population distributions of HFRS cases were described.
HFRS appeared to remain endemic in the country, while the majority of cases (accounting for 81.76% of total cases), were located in Shandong, Heilongjiang, Liaoning, Hebei, Shaanxi, Hunan, Jilin and Zhejiang provinces. The occurrence of HFRS appeared to be seasonal, with two peaks in spring season and autumn/winter season, with 10.00% of the cases occurred in these peak months. The incidence rates were at a relatively low level because of the continuous decline of HFRS in the recent years. With age distribution, 0.97% were younger than 10, 96.71% were between 10 and 70, 87.32% were between 15 and 60, and 2.31% were older than 70. The proportion of male patients accounted for three quarters. Around 70.00% of the cases were farmers. Young and middle-aged male farmers were at high risk.
The descriptive study on epidemiological characteristics of HFRS in the recent years had provided scientific evidence for vaccination strategy, suggesting the key regions, sub-populations as well as types of vaccines be determined.
研究1998年至2007年中国肾综合征出血热(HFRS)的流行病学特征及疫苗接种策略。
收集并分析1998年至2007年期间全国HFRS患病率数据。描述HFRS病例的空间、时间和人群分布。
HFRS在我国仍呈地方性流行,大部分病例(占总病例数的81.76%)分布在山东、黑龙江、辽宁、河北、陕西、湖南、吉林和浙江等省。HFRS的发病呈季节性,在春季和秋冬季节出现两个高峰,10.00%的病例发生在这些高峰月份。由于近年来HFRS持续下降,发病率处于相对较低水平。从年龄分布来看,10岁以下占0.97%,10至70岁占96.71%,15至60岁占87.32%,70岁以上占2.31%。男性患者比例占四分之三。约70.00%的病例为农民。中青年男性农民为高危人群。
近年来对HFRS流行病学特征的描述性研究为疫苗接种策略提供了科学依据,建议确定重点地区、亚人群以及疫苗类型。