Hayes R, Mahon T, Masterson J, Owens A
Department of Radiology, St. Vincent's Hospital, Dublin 4, Ireland.
Invest Radiol. 1991 Aug;26(8):742-4. doi: 10.1097/00004424-199108000-00009.
The authors report a randomized, double-blind prospective trial comparing the effects of nonionic with ionic low-osmolar contrast media on erythrocyte aggregation. The study group comprised 40 consecutive patients with pathology necessitating selective angiography. Patients were examined using either ioxaglate 320, iohexol 350, or iopamidol 370. Erythrocyte aggregation was assessed both macroscopically and microscopically. Erythrocyte aggregation occurred more frequently in the iopamidol group (13 of 45 samples examined) than in the iohexol (4 of 46) or ioxaglate (5 of 51) groups (P = .002).
作者报告了一项随机、双盲前瞻性试验，比较非离子型与离子型低渗造影剂对红细胞聚集的影响。研究组包括40例因病情需要进行选择性血管造影的连续患者。使用碘克沙醇320、碘海醇350或碘帕醇370对患者进行检查。通过宏观和微观评估红细胞聚集情况。碘帕醇组（检查的45个样本中有13个）红细胞聚集比碘海醇组（46个样本中有4个）或碘克沙醇组（51个样本中有5个）更频繁（P = 0.002）。
