Cury Marcelo, Greenberg Roy K, Morales Jose P, Mohabbat Walid, Hernandez Adrian V
Department of Vascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
J Vasc Surg. 2009 Jan;49(1):4-10. doi: 10.1016/j.jvs.2008.08.088.
Aneurysms involving the supra-aortic vessels are rare but carry serious risk of embolization, thrombosis, and rupture. We describe our experience with the diagnosis, treatment strategies, and outcomes in patients with extended follow-up.
Data during a 17-year period (January 1990 to December 2007) was analyzed. We assessed age, gender, presenting symptoms, localization, pathologic diagnosis, type of procedures, complications, and survival.
A total of 74 patients were treated for supra-aortic aneurysms. Of all aneurysms treated, 63% were degenerative, 24% iatrogenic, 8% traumatic, 3% genetic, and 1% mycotic. The subclavian artery was most commonly affected (50%, 2/3 in the right side), followed by the common carotid (36%), internal carotid (10%), innominate (3%), and vertebral (1%). At the time of diagnosis, 52 patients (70%) were asymptomatic, but of those symptomatic 68% had an embolic event as a presenting symptom. Embolic episodes were more common in patients with smaller aneurysms (P < .006). Open surgery was performed in 77% of all cases, and the use of endovascular techniques became the predominant treatment modality over the last 4 years. Survival at 30 days was 100%. Five- and 10-year survival rates were 87% and 43%, respectively.
Most cases of supra-aortic aneurysm are asymptomatic and embolization as opposed to rupture represents the greatest risk to the patient. Most cases can be detected prior to symptoms. Endovascular repair is an emerging alternative of treatment and, with the current development of appropriate devices, will likely form the mainstay of therapy in the near future.
累及主动脉弓上血管的动脉瘤较为罕见,但具有栓塞、血栓形成和破裂的严重风险。我们描述了我们在患者诊断、治疗策略及长期随访结果方面的经验。
分析了17年期间(1990年1月至2007年12月)的数据。我们评估了年龄、性别、临床表现、病变部位、病理诊断、手术类型、并发症及生存率。
共有74例患者接受了主动脉弓上动脉瘤治疗。在所有接受治疗的动脉瘤中,63%为退行性病变,24%为医源性,8%为创伤性,3%为遗传性,1%为霉菌性。锁骨下动脉最常受累(50%,右侧占2/3),其次是颈总动脉(36%)、颈内动脉(10%)、无名动脉(3%)和椎动脉(1%)。诊断时,52例患者(70%)无症状,但有症状的患者中68%以栓塞事件为首发症状。栓塞事件在较小动脉瘤患者中更为常见(P < 0.006)。77%的病例进行了开放手术,在过去4年中,血管内技术的应用成为主要治疗方式。30天生存率为100%。5年和10年生存率分别为87%和43%。
大多数主动脉弓上动脉瘤病例无症状,与破裂相比,栓塞对患者构成的风险最大。大多数病例在出现症状之前即可被检测到。血管内修复是一种新兴的治疗选择,随着合适器械的不断发展,在不久的将来可能会成为主要的治疗方法。