Mohler Virginia L, Izzo Matthew M, House John K
Livestock Veterinary Teaching and Research Unit, Faculty of Veterinary Science, University of Sydney, PMB 4, Narellan Delivery Centre, Camden, NSW 2567, Australia.
Vet Clin North Am Food Anim Pract. 2009 Mar;25(1):37-54, vi. doi: 10.1016/j.cvfa.2008.10.009.
Salmonellae are endemic on most large intensive farms and salmonellosis is a common cause of neonatal morbidity and mortality. Disease and mortality usually reflect a variety of management events and environmental stressors that contribute to compromised host immunity and increased pathogen exposure. The diversity of salmonella serovars present on farms, and the potential for different serovars to possess different virulence factors, require the implementation of broad prophylactic strategies that are efficacious for all salmonellae. This article discusses strategies to promote host immunity and minimize pathogen exposure at the farm level. The benefits of control include a reduction in disease incidence and mortality, reduced drug and labor costs, and improved growth rates.
沙门氏菌在大多数大型集约化养殖场中呈地方性流行，沙门氏菌病是新生儿发病和死亡的常见原因。疾病和死亡率通常反映了多种管理因素和环境应激源，这些因素会导致宿主免疫力受损和病原体暴露增加。养殖场中存在的沙门氏菌血清型具有多样性，且不同血清型可能具有不同的毒力因子，因此需要实施对所有沙门氏菌均有效的广泛预防策略。本文讨论了在养殖场层面提高宿主免疫力和减少病原体暴露的策略。控制的益处包括疾病发病率和死亡率降低、药物和劳动力成本降低以及生长速度提高。
