Ocama P, Nambooze S, Opio C K, Shiels M S, Wabinga H R, Kirk G D
Department of Medicine, Makerere University, Kampala, Uganda.
Br J Cancer. 2009 Mar 10;100(5):799-802. doi: 10.1038/sj.bjc.6604893. Epub 2009 Jan 27.
Primary liver cancer (PLC) incidence trends from Africa are unknown. Using Kampala Cancer Registry data from 1960 to 1980 and 1991 to 2005, we identified 771 PLCs. Although rates were stable among men, PLC incidence among women increased >50%. Investigations of viral hepatitis, aflatoxin, obesity, and human immunodeficiency virus (HIV) may help to explain the increasing incidence of hepatocellular carcinomas (HCCs).
非洲原发性肝癌（PLC）的发病趋势尚不清楚。利用坎帕拉癌症登记处1960年至1980年以及1991年至2005年的数据，我们识别出771例原发性肝癌。尽管男性发病率保持稳定，但女性原发性肝癌发病率增长超过了50%。对病毒性肝炎、黄曲霉毒素、肥胖症和人类免疫缺陷病毒（HIV）的调查可能有助于解释肝细胞癌（HCC）发病率上升的原因。
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