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乌干达儿童及其母亲中的丙型肝炎病毒基因型4

Hepatitis C virus genotype 4 in Ugandan children and their mothers.

作者信息

Biggar Robert J, Ortiz-Conde Betty A, Bagni Rachel K, Bakaki Paul M, Wang Cheng-Dian, Engels Eric A, Mbulaiteye Sam M, Ndugwa Christopher M

机构信息

Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA.

出版信息

Emerg Infect Dis. 2006 Sep;12(9):1440-3. doi: 10.3201/eid1209.041068.

DOI:10.3201/eid1209.041068
PMID:17073099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3294722/
Abstract

In Kampala, Uganda, in 2001, hepatitis C virus antibodies were found in 27 (4%) of 603 children and in 62 (12%) of 525 of their mothers. However, only approximately 10% of positive results were confirmed by reverse transcription-PCR, which suggests frequent false-positive results or viral clearance. All sequenced types were genotype 4.

摘要

2001年,在乌干达坎帕拉,603名儿童中有27名(4%)、其525名母亲中有62名(12%)检测出丙型肝炎病毒抗体。然而,只有约10%的阳性结果通过逆转录聚合酶链反应得到确认,这表明存在频繁的假阳性结果或病毒清除情况。所有测序类型均为4型基因型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a47/3294722/375c290b4ffd/04-1068-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a47/3294722/38ac607528cf/04-1068-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a47/3294722/375c290b4ffd/04-1068-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a47/3294722/38ac607528cf/04-1068-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a47/3294722/375c290b4ffd/04-1068-F2.jpg

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