Heikkinen E, Lumme J
Department of Genetics, University of Oulu, Finland.
Heredity (Edinb). 1991 Aug;67 ( Pt 1):1-11. doi: 10.1038/hdy.1991.58.
The sterility of interspecific hybrids between the sibling species Drosophila virilis and D. lummei was tested in reciprocal F1s and different second generation combinations of cytoplasm, sex chromosomes and autosomes. Males with motile sperm and females with at least one mature egg were scored as fertile. When D. virilis was the mother, about 5 per cent of the F1 male progeny was sterile, the reason being that the X of D. virilis was weakly incompatible with the heterozygous second, fourth and fifth chromosomes. The F1 males carrying the X chromosome of D. lummei were all fertile. The X chromosome of D. lummei, and in particular its species-specific double inversion In(1)a + b, nevertheless caused sterility in 70 per cent of males in the presence of homozygous autosomes of D. virilis. Sterility was rare among the females, although some weakly disadvantageous X versus autosome and autosome versus autosome interactions were detected. The male and female hybrid sterilities were based on different genetic systems. The results emphasize the central role of the X chromosome in hybrid male sterility.
在同胞物种果蝇（Drosophila virilis）和鲁氏果蝇（D. lummei）之间的种间杂交不育性，在正反交F1代以及细胞质、性染色体和常染色体的不同第二代组合中进行了测试。具有活动精子的雄性和至少有一个成熟卵子的雌性被视为可育。当果蝇作为母本时，约5%的F1代雄性后代不育，原因是果蝇的X染色体与杂合的第二、第四和第五染色体存在弱不相容性。携带鲁氏果蝇X染色体的F1代雄性均为可育。然而，在存在果蝇纯合常染色体的情况下，鲁氏果蝇的X染色体，特别是其物种特异性的双倒位In(1)a + b，导致70%的雄性不育。雌性中的不育情况很少见，尽管检测到一些X与常染色体以及常染色体与常染色体之间的弱不利相互作用。雄性和雌性杂种不育基于不同的遗传系统。结果强调了X染色体在杂种雄性不育中的核心作用。
