Falileeva L I, Mitrofanov V G
Genetika. 1997 Apr;33(4):458-63.
Genetic analysis of male sterility in Drosophila virilis x D. lummei hybrids was performed. It was shown that hybrid male sterility was caused mainly by incompatibility of sex chromosomes X and Y and homozygous chromosome 2 of D. virilis with other autosomes of D. lummei. Genes of chromosomes 3 and 5 enhanced sterility whereas genes of chromosome 4 suppressed its development. Factors controlling hybrid male sterility were demonstrated to have a recessive type of inheritance. At 17 degrees C, chromosome 6 of D. lummei was eliminated in F1 hybrids of the cross female D. virilis x male D. lummei. At 17 degrees C and 25 degrees C, sterility of the F1 hybrid males was 96% and 9%, respectively. Thus, two isolation mechanisms-elimination of chromosome 6 and male sterility-can simultaneously operate in F1. In addition to the region of the species-specific inversion In 1(a+b), factors controlling male sterility were mapped to the vermillion region of the X chromosome.
对果蝇属强壮果蝇（Drosophila virilis）与卢氏果蝇（D. lummei）杂交种的雄性不育进行了遗传分析。结果表明，杂种雄性不育主要是由强壮果蝇的X和Y性染色体以及2号纯合染色体与卢氏果蝇的其他常染色体不亲和所致。3号和5号染色体的基因增强了不育性，而4号染色体的基因则抑制了其发育。控制杂种雄性不育的因子表现出隐性遗传类型。在17摄氏度时，在雌性强壮果蝇与雄性卢氏果蝇杂交的F1杂种中，卢氏果蝇的6号染色体被消除。在17摄氏度和25摄氏度时，F1杂种雄性的不育率分别为96%和9%。因此，两种隔离机制——6号染色体消除和雄性不育——可以在F1中同时起作用。除了物种特异性倒位In 1(a+b)区域外，控制雄性不育的因子被定位到X染色体的朱红色区域。
