The structure of heneicomycin.
作者信息
Dewey R S, Hensens O D, Douglas A W, Albers-Schönberg G
机构信息
Merck Sharp and Dohme Research Laboratories, Rahway, NJ 07065.
出版信息
J Antibiot (Tokyo). 1991 Aug;44(8):838-43. doi: 10.7164/antibiotics.44.838.
PMID:1917698
Abstract
The antibiotic heneicomycin (1), C44H62N2O11, was isolated from cultures of Streptomyces filipinensis as an amorphous yellow powder. Mass spectral and NMR analysis showed the compound to be a deoxy modification of aurodox (2), a member of the elfamycin antibiotic family. A marked change in mass spectral fragmentation compared to aurodox and 1H NMR couplings indicated the absence of the hydroxyl at position 30 of aurodox (position 3 of the tetrahydropyran).
摘要
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