Morrish Donald W, Beaupre Lauren A, Bell Neil R, Cinats John G, Hanley David A, Harley Charles H, Juby Angela G, Lier Douglas A, Maksymowych Walter P, Majumdar Sumit R
University of Alberta, Edmonton, Alberta, Canada.
Arthritis Rheum. 2009 Feb 15;61(2):209-15. doi: 10.1002/art.24097.
We previously demonstrated that a case manager intervention improved osteoporosis (OP) treatment within 6 months of hip fracture compared with usual care. The second phase of the randomized trial compared a less intensive intervention, facilitated bone mineral density (BMD) testing, with usual care and the case manager intervention.
We initially randomized 220 hip fracture patients to either an OP case manager intervention or usual care. After completing the original trial at 6 months postfracture, usual care patients were reallocated to facilitated BMD testing; BMD tests were arranged and results sent to primary care physicians. Main outcomes (bisphosphonate treatment, BMD tests, receipt of appropriate care) were reascertained 1 year following hip fracture and compared with outcomes achieved by the OP case manager intervention and usual care.
Compared with usual care, facilitated BMD testing increased testing from 29% to 68% (P < 0.001), bisphosphonate use from 22% to 38% (P < 0.001), and receipt of appropriate care from 26% to 45% (P < 0.001). The more intensive (70 versus 30 minutes) and expensive ($56 versus $24 Canadian per patient) OP case manager intervention led to significantly higher bisphosphonate use (54% versus 38%; P = 0.03), receipt of appropriate care (71% versus 45%; P < 0.001), and more BMD testing (80% versus 68%; P = 0.06) than usual care followed by facilitated BMD testing.
Compared with usual care, 2 different inexpensive interventions resulted in significant increases in appropriate management of OP after hip fracture. The magnitude of improvements achieved was directly related to the intensity of the interventions.
我们之前证明,与常规护理相比,病例管理干预在髋部骨折后6个月内改善了骨质疏松症(OP)的治疗。随机试验的第二阶段将强度较低的干预措施(促进骨密度(BMD)检测)与常规护理及病例管理干预进行了比较。
我们最初将220例髋部骨折患者随机分为接受OP病例管理干预或常规护理。在骨折后6个月完成原始试验后,常规护理患者被重新分配接受促进BMD检测;安排了BMD检测,并将结果发送给初级保健医生。在髋部骨折1年后重新确定主要结局(双膦酸盐治疗、BMD检测、接受适当护理),并与OP病例管理干预和常规护理所取得的结局进行比较。
与常规护理相比,促进BMD检测使检测率从29%提高到68%(P<0.001),双膦酸盐的使用从22%增加到38%(P<0.001),接受适当护理的比例从26%提高到45%(P<0.001)。强度更高(70分钟对30分钟)且成本更高(每位患者56加元对24加元)的OP病例管理干预导致双膦酸盐的使用显著增加(54%对38%;P=0.03),接受适当护理的比例更高(71%对45%;P<0.001),且BMD检测比常规护理后进行促进BMD检测更多(80%对68%;P=0.06)。
与常规护理相比,两种不同的低成本干预措施在髋部骨折后OP的适当管理方面均有显著增加。所取得的改善程度与干预强度直接相关。