Cui Haifeng, Li Peng, Chai Zhuo, Zheng Changwu, Zhao Gang, Zhu Shizheng
Laboratory of Modern Synthetic Organic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, People's Republic of China.
J Org Chem. 2009 Feb 6;74(3):1400-2. doi: 10.1021/jo8023818.
A series of fluorinated flavanones were synthesized in moderate to good yields with excellent diastereoselectivities under mild reaction conditions via a one-pot tandem procedure involving a proline-catalyzed Knoevenagel condensation, a Michael addition, and an electrophilic fluorination by NFSI.
通过一锅串联反应，在温和的反应条件下，以脯氨酸催化的Knoevenagel缩合、迈克尔加成以及NFSI亲电氟化反应，以中等至良好的产率和优异的非对映选择性合成了一系列氟化黄烷酮。
