Sabbagh Zohreh, Vatanparast Hassanali
College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Nutr Rev. 2009 Feb;67(2):105-8. doi: 10.1111/j.1753-4887.2008.00146.x.
Low intake of dietary calcium is related to bone loss and fragility fracture in older adults, especially postmenopausal women. Contradictory findings have been reported from studies that investigated the association between calcium supplementation and hypertension and the risk of stroke and cardiovascular disease. Misinterpretation of findings from studies that are not primarily designed to address these issues might overshadow the benefits of dietary calcium. Until well-designed studies address the current uncertainties, the possible detrimental effect (e.g., hypercalcemia and its complications) of higher-than-recommended calcium intake should be balanced against the likely benefits of calcium on bone, particularly in elderly women.
老年人，尤其是绝经后女性，膳食钙摄入量低与骨质流失和脆性骨折有关。关于钙补充剂与高血压以及中风和心血管疾病风险之间关联的研究报告了相互矛盾的结果。对并非主要为解决这些问题而设计的研究结果的错误解读可能会掩盖膳食钙的益处。在设计良好的研究解决当前的不确定性之前，应权衡高于推荐量的钙摄入可能产生的有害影响（如高钙血症及其并发症）与钙对骨骼可能带来的益处，尤其是对老年女性而言。
