Palombo G, Stella N, Faraglia V, Rizzo L, Capuano F, Sinatra R, Taurino M
Division of Vascular Surgery, Sant'Andrea Hospital La Sapienza, Second Faculty, University of Rome, Rome, Italy.
J Cardiovasc Surg (Torino). 2009 Feb;50(1):49-54.
Optimal strategy (staged or combined) for the treatment of patients with concurrent severe carotid and cardiac disease is still controversial. Moreover, carotid artery stenting (CAS), has become a valid alternative to carotid endarterectomy (CEA) and has been proposed for the treatment of cardiac patients. The authors report the preliminary results of a new therapeutic strategy consisting in combined CAS and cardiac surgery.
An initial series of 22 patients underwent combined CAS and cardiac surgery in the same operating room and under general anesthesia. All filter-protected CAS procedures were performed under only heparin and aspirin. A cervical approach (3-cm cervicotomy) was used in patients with documented vessel tortuosity or severe aorto-iliac occlusive arteriopathy. In all the other cases a femoral access was used. A double antiplatelet regimen was initiated in the early postoperative period, once major bleedings were excluded.
Among the 22 patients who underwent this combined procedure, no deaths, no myocardial infarctions and one controlateral stroke (overall complication rate: 4.5%) were observed. This stroke was observed after transcervical CAS, coronary artery bypass and mitral valve replacement. No major postoperative bleedings nor stent thrombosis were observed.
Combined carotid stenting and cardiac surgery, performed in the same operating room under only heparin and aspirin, seems a safe and effective strategy for the treatment of patients with concomitant carotid and cardiac disease.
对于同时患有严重颈动脉和心脏疾病的患者,最佳治疗策略(分期或联合)仍存在争议。此外,颈动脉支架置入术(CAS)已成为颈动脉内膜切除术(CEA)的有效替代方法,并已被提议用于治疗心脏病患者。作者报告了一种由CAS和心脏手术联合组成的新治疗策略的初步结果。
最初的22例患者在同一手术室全身麻醉下接受了CAS和心脏手术联合治疗。所有使用滤器保护的CAS手术仅在肝素和阿司匹林治疗下进行。对于有血管迂曲或严重主-髂动脉闭塞性动脉病变记录的患者,采用颈部入路(3厘米颈部切口)。在所有其他情况下,采用股动脉入路。术后早期一旦排除大出血,即开始双重抗血小板治疗方案。
在接受这种联合手术的22例患者中,未观察到死亡、心肌梗死,仅发生1例对侧卒中(总并发症发生率:4.5%)。该卒中发生在经颈部CAS、冠状动脉搭桥和二尖瓣置换术后。未观察到术后大出血和支架血栓形成。
在同一手术室仅在肝素和阿司匹林治疗下进行的CAS与心脏手术联合,似乎是治疗合并颈动脉和心脏疾病患者的一种安全有效的策略。