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重度并发严重颈动脉和冠状动脉疾病患者的血运重建策略:“无法前进就是后退的理由” 。

Revascularization strategy in patients with severe concurrent severe carotid and coronary artery disease: ''failure to move forward is reason to regress''.

作者信息

Van Der Heyden J, Suttorp M J, Schepens M A A M

机构信息

Department of Interventional Cardiology, St.-Antonius Hospital, Nieuwegein, The Netherlands.

出版信息

J Cardiovasc Surg (Torino). 2009 Feb;50(1):55-62.

Abstract

In the absence of randomized trials, the optimal management of patients with concomitant carotid and coronary artery disease remains disputable. The initial studies of combined or staged carotid endarterectomy in these patients were conceived in an attempt to reduce perioperative mortality. Although encouraging results have been reported with combined carotid endarterectomy and cardiac surgery, this combination requires long operative times and remains a surgical challenge. Recent studies have shown that carotid angioplasty and stenting prior to cardiac surgery is a feasible and effective minimal invasive technique. However, the effect of carotid stenting on the incidence of death and stroke after cardiac surgery is indistinct. Carotid stenting followed by cardiac surgery may provide a valuable treatment for patients with combined carotid and cardiac disease. The high rate of freedom from death and stroke during follow-up supports the long-term durability of this strategy. In the present review, we highlight the available data on carotid stenting and cardiac surgery.

摘要

在缺乏随机试验的情况下,合并颈动脉和冠状动脉疾病患者的最佳治疗方案仍存在争议。这些患者联合或分期行颈动脉内膜切除术的初步研究旨在降低围手术期死亡率。尽管有报道称颈动脉内膜切除术与心脏手术联合应用取得了令人鼓舞的结果,但这种联合手术需要较长的手术时间,仍然是一项外科挑战。最近的研究表明,在心脏手术前行颈动脉血管成形术和支架置入术是一种可行且有效的微创技术。然而,颈动脉支架置入术对心脏手术后死亡和卒中发生率的影响尚不明确。先进行颈动脉支架置入术再进行心脏手术可能为合并颈动脉和心脏疾病的患者提供一种有价值的治疗方法。随访期间较低的死亡和卒中发生率支持了该策略的长期有效性。在本综述中,我们重点介绍了关于颈动脉支架置入术和心脏手术的现有数据。

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