Kyanous Stavros Hospital, Viziis 1, 54636 Thessaloniki, Greece.
J Vasc Surg. 2011 May;53(5):1237-41. doi: 10.1016/j.jvs.2010.11.049. Epub 2011 Jan 17.
The optimal management of the patients requiring cardiac surgery with concomitant severe carotid disease remains a controversy. The traditional approach involves staged or combined carotid endarterectomy and cardiac surgery. This study evaluated the feasibility and safety of angioplasty and stenting for the treatment of carotid stenoses concomitantly to cardiac operations to reduce the risk of perioperative stroke.
All patients scheduled for cardiac surgery were screened preoperatively by color duplex ultrasonography for carotid disease. Carotid stenoses ≥60% in symptomatic patients and ≥70% in asymptomatic patients were treated using carotid artery stenting (CAS) under local anesthesia immediately before the open heart surgery. Cerebral protection devices were used in all cases. Patients did not receive aspirin or clopidogrel before the procedure. In a prospective, nonrandomized study, we analyzed 90 consecutive patients requiring cardiac surgery with concomitant severe carotid artery disease who underwent one stage CAS and cardiac surgery.
Despite the high baseline risk profile, our results were encouraging. Carotid stenting was successful in all patients. No neurologic complications occurred during the carotid stenting procedures. The 30-day death/stroke rate was 2.2% (one death, one contralateral stroke). No myocardial infarction occurred. The carotid restenosis rate was zero during the intermediate-term follow-up.
In our experience, CAS followed immediately by cardiac surgery is safe and represents a reasonable option for selected patients presenting with severe carotid and coronary disease.
同时患有严重颈动脉疾病的心脏手术患者的最佳治疗方案仍存在争议。传统的治疗方法包括分期或联合颈动脉内膜切除术和心脏手术。本研究评估了在心脏手术同时进行血管成形术和支架置入术治疗颈动脉狭窄以降低围手术期卒中风险的可行性和安全性。
所有计划接受心脏手术的患者均在术前通过彩色双功能超声筛查颈动脉疾病。有症状的患者颈动脉狭窄≥60%,无症状患者颈动脉狭窄≥70%,在体外循环心脏手术前在局部麻醉下立即进行颈动脉支架置入术(CAS)。所有病例均使用脑保护装置。患者在术前未服用阿司匹林或氯吡格雷。在一项前瞻性、非随机研究中,我们分析了 90 例连续的同时患有严重颈动脉疾病的需要心脏手术的患者,这些患者接受了同期的 CAS 和心脏手术。
尽管基线风险较高,但我们的结果令人鼓舞。所有患者的颈动脉支架置入术均成功。颈动脉支架置入术中无神经并发症发生。30 天死亡率/卒中率为 2.2%(1 例死亡,1 例对侧卒中)。无心肌梗死发生。在中期随访期间,颈动脉再狭窄率为零。
根据我们的经验,CAS 紧随心脏手术后进行是安全的,对于同时患有严重颈动脉和冠状动脉疾病的选定患者来说是一个合理的选择。