Hagen Erika W, Sadek-Badawi Mona, Albanese Aggie, Palta Mari
Department of Population Health Sciences, University of Wisconsin, Madison, WI, USA.
WMJ. 2008 Nov;107(7):320-6.
Improvements in neonatal care over the past 3 decades have increased survival of infants at lower birthweights and gestational ages. However, outcomes and practices vary considerably between hospitals.
To describe maternal and infant characteristics, neonatal intensive care units (NICU) practices, morbidity, and mortality in Wisconsin NICUs, and to compare outcomes in Wisconsin to the National Institute of Child Health and Human Development network of large academic medical center NICUs.
The Newborn Lung Project Statewide Cohort is a prospective observational study of all very low birthweight (< or =1500 grams) infants admitted during 2003 and 2004 to the 16 level III NICUs in Wisconsin. Anonymous data were collected for all admitted infants (N=1463). Major neonatal morbidities, including bronchopulmonary dysplasia (BPD), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), and retinopathy of prematurity (ROP) were evaluated.
The overall incidence of BPD was 24% (8%-56% between NICUs); IVH incidence was 23% (9%-41%); the incidence of NEC was 7% (0%-21%); and the incidence of grade III or higher ROP was 10% (0%-35%).
The incidence rates of major neonatal morbidities in Wisconsin were similar to those of a national network of academic NICUs.
在过去30年中,新生儿护理水平的提高增加了低出生体重和低胎龄婴儿的存活率。然而,不同医院的治疗结果和做法差异很大。
描述威斯康星州新生儿重症监护病房(NICU)中母婴的特征、NICU的治疗方法、发病率和死亡率,并将威斯康星州的治疗结果与国家儿童健康与人类发展研究所大型学术医疗中心NICU网络的结果进行比较。
全州新生儿肺部项目队列研究是一项对2003年和2004年入住威斯康星州16家三级NICU的所有极低出生体重(≤1500克)婴儿进行的前瞻性观察研究。收集了所有入院婴儿(N = 1463)的匿名数据。评估了主要的新生儿疾病,包括支气管肺发育不良(BPD)、脑室内出血(IVH)、坏死性小肠结肠炎(NEC)和早产儿视网膜病变(ROP)。
BPD的总体发病率为24%(各NICU之间为8% - 56%);IVH发病率为23%(9% - 41%);NEC发病率为7%(0% - 21%);III级或更高等级ROP的发病率为10%(0% - 35%)。
威斯康星州主要新生儿疾病的发病率与全国学术NICU网络的发病率相似。