Palta Mari, LeCaire Tamara
University of Wisconsin-Madison Department of Population Health Sciences, 610 Walnut St, Room 689, Madison, WI 53726-2397, USA.
WMJ. 2009 Aug;108(5):231-5.
The Wisconsin Diabetes Registry Study is a Wisconsin cohort of patients with type 1 diabetes, who were diagnosed in 1987-1992 and actively followed. The study provides patients and health care professionals with better prognostic information and helps identify aspects of diabetes management that need improvement.
To describe diabetes management and acute and chronic complications from the time of diagnosis.
All incident cases diagnosed at age <30 in 28 counties were eligible and 590 enrolled. A baseline interview, blood sample kits, biannual/annual questionnaires and study examinations at 4, 7, 9, 14, and 20 years duration were administered.
Diabetes management indicators, general health, and acute and chronic complications.
Glycemic control was poor in adolescence, but improved with age. A high percentage of individuals do not meet treatment standards for blood pressure and lipid profile. Self-reported health deteriorated with age, and body mass index was similar to that of the general US population. Chronic complications were present at 15-20 years, but tended to be relatively mild.
There is room for improvement in diabetes management, especially in meeting goals for blood pressure and lipid profile. Nonetheless, individuals with type 1 diabetes can be offered a more optimistic prognosis than in the past.
威斯康星糖尿病登记研究是对1987年至1992年确诊的1型糖尿病患者的威斯康星队列进行的研究，并对其进行了积极随访。该研究为患者和医疗保健专业人员提供了更好的预后信息，并有助于确定糖尿病管理中需要改进的方面。
描述从诊断时起的糖尿病管理以及急性和慢性并发症。
在28个县中，所有年龄<30岁的新发病例均符合条件，共有590人入组。进行了基线访谈、血样采集试剂盒、每半年/每年一次的问卷调查以及在病程4年、7年、9年、14年和20年时的研究检查。
糖尿病管理指标、总体健康状况以及急性和慢性并发症。
青少年期血糖控制较差，但随着年龄增长有所改善。很大一部分人未达到血压和血脂谱的治疗标准。自我报告的健康状况随年龄恶化，体重指数与美国普通人群相似。15至20年时出现慢性并发症，但往往相对较轻。
糖尿病管理仍有改进空间，尤其是在达到血压和血脂谱目标方面。尽管如此，与过去相比，1型糖尿病患者可以获得更乐观的预后。
