Brown R
Tufts University, Boston, Mass.
Hosp Pract (Off Ed). 1991 Sep;26 Suppl 5:37-42; discussion 59-62. doi: 10.1080/21548331.1991.11707742.
One gram once daily of ceftriaxone is as effective as 2 gm for the common causative organisms of community-acquired and nosocomial pneumonias. It should not be used alone against L. pneumophila, the TWAR pneumoniae, and possibly anaerobic pathogens. Preliminary study suggests that a regimen of 500 mg a day may be effective in selected patients with simple pneumonias caused by sensitive pathogens. Ceftriaxone is safe, well tolerated, and cost-effective, which means it can play a significant therapeutic role in nursing homes and other long-term care facilities as well as in outpatient therapy.
对于社区获得性肺炎和医院获得性肺炎的常见致病微生物，每日一次1克头孢曲松的疗效与2克相同。它不应单独用于治疗嗜肺军团菌、TWAR肺炎支原体以及可能的厌氧性病原体。初步研究表明，对于由敏感病原体引起的单纯性肺炎的特定患者，每日500毫克的治疗方案可能有效。头孢曲松安全、耐受性好且具有成本效益，这意味着它在疗养院和其他长期护理机构以及门诊治疗中都能发挥重要的治疗作用。
