Spiegel B M R, Farid M, van Oijen M G H, Laine L, Howden C W, Esrailian E
Department of Gastroenterology, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
Aliment Pharmacol Ther. 2009 Apr 15;29(8):871-81. doi: 10.1111/j.1365-2036.2009.03935.x. Epub 2009 Jan 15.
Although 'best practice' guidelines for dyspepsia management have been disseminated, it remains unclear whether providers adhere to these guidelines.
To compare adherence to 'best practice' guidelines among dyspepsia experts, community gastroenterologists and primary-care providers (PCPs).
We administered a vignette survey to elicit knowledge and beliefs about dyspepsia including a set of 16 best practices, to three groups: (i) dyspepsia experts; (ii) community gastroenterologists and (iii) PCPs.
The expert, community gastroenterologist and PCP groups endorsed 75%, 73% and 57% of best practices respectively. Gastroenterologists were more likely to adhere with guidelines than PCPs (P < 0.0001). PCPs were more likely to define dyspepsia incorrectly, overuse radiographic testing, delay endoscopy, treat empirically for Helciobacter pylori without confirmatory testing and avoid first-line proton pump inhibitors (PPIs). PCPs had more concerns about adverse events with PPIs [e.g. osteoporosis (P = 0.04), community-acquired pneumonia (P = 0.01)] and higher level of concern predicted lower guideline adherence (P = 0.04).
Gastroenterologists are more likely than PCPs to comply with best practices in dyspepsia, although compliance remains incomplete in both groups. PCPs harbour more concerns regarding long-term PPI use and these concerns may affect therapeutic decision making. This suggests that best practices have not been uniformly adopted and persistent guideline-practice disconnects should be addressed.
尽管已发布消化不良管理的“最佳实践”指南,但尚不清楚医疗服务提供者是否遵循这些指南。
比较消化不良专家、社区胃肠病学家和初级保健提供者(PCP)对“最佳实践”指南的遵循情况。
我们对三组人员进行了一项情景调查,以了解他们对消化不良的知识和信念,包括一组16项最佳实践,这三组人员分别为:(i)消化不良专家;(ii)社区胃肠病学家;(iii)初级保健提供者。
专家组、社区胃肠病学家组和初级保健提供者组分别认可了75%、73%和57%的最佳实践。胃肠病学家比初级保健提供者更有可能遵循指南(P<0.0001)。初级保健提供者更有可能错误定义消化不良、过度使用影像学检查、延迟内镜检查、在未进行确诊检测的情况下经验性治疗幽门螺杆菌以及避免使用一线质子泵抑制剂(PPI)。初级保健提供者对PPI的不良事件更为担忧[如骨质疏松(P = 0.04)、社区获得性肺炎(P = 0.01)],而更高的担忧程度预示着更低的指南遵循率(P = 0.04)。
胃肠病学家比初级保健提供者更有可能遵循消化不良的最佳实践,尽管两组的遵循情况均不完全。初级保健提供者对长期使用PPI更为担忧,这些担忧可能会影响治疗决策。这表明最佳实践尚未得到统一采用,应解决持续存在的指南与实践脱节问题。