Bestetti Reinaldo B, Martins Cláudia A, Cardinalli-Neto Augusto
Department of Cardiology and Cardiovascular Surgery, Hospital de Base, Faculty of Medicine of São José do Rio Preto, Brazil.
Int J Cardiol. 2009 May 1;134(1):9-16. doi: 10.1016/j.ijcard.2008.12.197. Epub 2009 Jan 30.
Working in the Brazilian backland, Chagas described a new disease. He discovered the etiologic agent, the vector, the reservoir, the acute stage, the several clinical aspects of the chronic stage (particularly the heart disease), role of autoimmunity in its pathogenesis, and anticipated the social impact of the disease. Chagas was nominated to Nobel Prize twice: in 1913, and in 1921. In 1913, Richet won the prize because his work on anaphylaxis. In 1921, no one received the Nobel Prize. It is believed that detraction of Chagas' work at the National Academy of Medicine, made by jealousy, mediocrity, and political rivalries can be maculated the image of the scientist. Furthermore, misperception of Chagas' work may also have led the Nobel Committee not to award him. One-hundred years after the discovery, we can appreciate the greatness of the discovery of Carlos Chagas, never seem in the realm of biological research. Time to make justice, therefore, has finally come.
在巴西内陆地区工作时，查加斯描述了一种新疾病。他发现了病原体、传播媒介、宿主、急性期以及慢性期的几个临床方面（尤其是心脏病），自身免疫在其发病机制中的作用，并预见了该疾病的社会影响。查加斯两次获得诺贝尔奖提名：一次是在1913年，另一次是在1921年。1913年，里歇因在过敏反应方面的工作而获奖。1921年，无人获得诺贝尔奖。人们认为，国家医学科学院中因嫉妒、平庸和政治竞争而对查加斯工作的诋毁，可能玷污了这位科学家的形象。此外，对查加斯工作的误解也可能导致诺贝尔委员会未授予他奖项。在发现该疾病一百年后，我们能够认识到卡洛斯·查加斯的发现之伟大，这在生物学研究领域中前所未见。因此，伸张正义的时候终于到了。
