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本国的先知:卡洛斯·查加斯与诺贝尔奖

Prophet in his own country: Carlos Chagas and the Nobel Prize.

作者信息

Lewinsohn Rachel

机构信息

Faculty of Medical Sciences, State University of Campinas (SP)-UNICAMP, Brazil.

出版信息

Perspect Biol Med. 2003 Fall;46(4):532-49. doi: 10.1353/pbm.2003.0078.

Abstract

In 1909, Carlos Chagas (1878-1934) discovered a new protozoon, Trypanosoma cruzi, and the (previously unknown) disease that it causes. Within a few months, virtually single-handed, he described the pathogen, its vector, and the clinical features of American trypanosomiasis (Chagas disease), a feat unique in medical history. He headed the Oswaldo Cruz Institute after the death of its founder (1917) until his own death; and from 1920 until 1926 he also directed the Brazilian Department of Public Health. His discovery brought him worldwide acclaim, but at home antagonism against Chagas, muted for years, finally flared up in a campaign that was acted out in the 1921-22 plenary sessions of the National Academy of Medicine. Chagas's name was repeatedly proposed for the Nobel Prize but he never received it; this hostile campaign may have been instrumental in costing him the award.

摘要

1909年,卡洛斯·查加斯(1878 - 1934)发现了一种新的原生动物——克氏锥虫,以及它所引发的(此前未知的)疾病。在短短几个月内,几乎是他独自一人,描述了这种病原体、其传播媒介以及美洲锥虫病(查加斯病)的临床特征,这在医学史上是独一无二的壮举。在奥斯瓦尔多·克鲁兹研究所的创始人去世后(1917年),他领导该研究所直至自己去世;1920年至1926年期间,他还负责巴西公共卫生部。他的发现为他赢得了全球赞誉,但在国内,多年来对查加斯的敌意最终在一场运动中爆发,这场运动在1921 - 1922年国家医学科学院的全会上上演。查加斯的名字多次被提名为诺贝尔奖,但他从未获奖;这场敌对运动可能对他未能获奖起到了推波助澜的作用。

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