Pradel Françoise G, Suwannaprom Puckwipa, Mullins C Daniel, Sadler John, Bartlett Stephen T
Department of Pharmaceutical Health Services Research, University of Maryland Baltimore School of Pharmacy, 220 Arch Street, Office level one, Baltimore, MD 21201, USA.
Prog Transplant. 2008 Dec;18(4):263-72. doi: 10.1177/152692480801800409.
Given the shortage of kidneys available for transplantation, a community-based intervention trial was implemented to assess the impact of an educational program on patients' access to live donor kidney transplantation (LDKT).
To compare the short-term impact of a basic intervention and an enhanced intervention on patients' readiness to pursue LDKT. DEGISN: Baseline data and data from 1 week after interventions were analyzed.
214 transplant-eligible hemodialysis patients attending 14 dialysis facilities in Maryland, Virginia, and Pennsylvania.
In the basic intervention, 107 patients watched a 10-minute videotape on the experience of recipients and live donors of a kidney. In the enhanced intervention, 107 patients watched the same videotape and had a discussion with a health educator on the risks and benefits of LDKT, who could be a donor, and how to address the barriers they were encountering when seeking a live kidney donor.
Patient reported whether they were considering LDKT, had talked with family or friends about LDKT, and had asked someone for a kidney.
Over half of transplant-eligible patients were not pursuing LDKT at baseline (64% in the basic intervention group, 61% in the enhanced intervention group). One week after the intervention, the odds of considering LDKT were higher among African Americans (odds ratio [OR], 2.28; confidence interval [CI], 1.22-4.25), younger patients (OR, 0.94; CI, 0.91-0.97), and patients who spent less time on dialysis (OR, 0.90; CI, 0.83-0.97). The odds of asking for a kidney were higher among African Americans (OR, 4.94; CI, 2.54-9.60) and patients who perceived they were in poor to fair health (OR, 3.30; CI, 1.12-9.67).
Although both interventions helped patients consider LDKT and ask for a kidney, more time and expanded educational content might be needed to facilitate patients' discussion about LDKT with their loved ones.
鉴于可用于移植的肾脏短缺,开展了一项基于社区的干预试验,以评估一项教育计划对患者获得活体供肾移植(LDKT)的影响。
比较基本干预和强化干预对患者准备接受LDKT的短期影响。
分析基线数据和干预后1周的数据。
214名符合移植条件的血液透析患者,他们在马里兰州、弗吉尼亚州和宾夕法尼亚州的14个透析机构接受治疗。
在基本干预中,107名患者观看了一段10分钟的关于肾脏受者和活体供者经历的录像带。在强化干预中,107名患者观看了相同的录像带,并与一名健康教育工作者讨论了LDKT的风险和益处、谁可以成为供者以及如何克服他们在寻找活体肾脏供者时遇到的障碍。
患者报告他们是否在考虑接受LDKT、是否与家人或朋友谈论过LDKT以及是否向某人请求提供肾脏。
超过一半符合移植条件的患者在基线时未寻求接受LDKT(基本干预组为64%,强化干预组为61%)。干预后1周,非裔美国人(优势比[OR],2.28;置信区间[CI],1.22 - 4.25)、年轻患者(OR,0.94;CI,0.91 - 0.97)以及透析时间较短的患者(OR,0.90;CI,0.83 - 0.97)考虑接受LDKT的几率更高。非裔美国人(OR,4.94;CI,2.54 - 9.60)以及认为自己健康状况为差到一般的患者(OR,3.30;CI,1.12 - 9.67)请求提供肾脏的几率更高。
尽管两种干预措施都有助于患者考虑接受LDKT并请求提供肾脏,但可能需要更多时间和扩展教育内容来促进患者与亲人讨论LDKT。