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利用金纳米粒子进行生物启发式比色法检测汞离子和铅离子重金属离子

Bio-inspired colorimetric detection of Hg2+ and Pb2+ heavy metal ions using Au nanoparticles.

作者信息

Knecht Marc R, Sethi Manish

机构信息

Department of Chemistry, University of Kentucky, 101 Chemistry-Physics Building, Lexington, KY 40506-0055, USA.

出版信息

Anal Bioanal Chem. 2009 May;394(1):33-46. doi: 10.1007/s00216-008-2594-7. Epub 2009 Feb 3.

Abstract

Heavy metal ions are highly toxic species which can cause long-term damage to biological systems. These species are known to disrupt biological events at the cellular level, cause significant oxidative damage, and are carcinogens. The production of simple, in-field detection methods that are highly sensitive for these cations is highly desirable in response to global pollution. In that regard, bio-inspired colorimetric sensing systems have been developed to detect Hg(2+) and Pb(2+), and other cations, down to nmol L(-1) concentrations. The benefits of these systems, which are reviewed herein, include cost-effective production, facile usage, and a visual color change for the detection method. Such advantages are significant positive steps for heavy metal ion detection, especially in regions where sophisticated laboratory studies are prohibited.

摘要

重金属离子是剧毒物质,会对生物系统造成长期损害。已知这些物质会在细胞水平上扰乱生物活动,造成严重的氧化损伤,并且是致癌物。鉴于全球污染问题,非常需要开发出对这些阳离子具有高灵敏度的简单现场检测方法。在这方面,已经开发出受生物启发的比色传感系统,用于检测汞离子(Hg(2+))、铅离子(Pb(2+))及其他阳离子,检测下限可达纳摩尔每升(nmol L(-1))浓度。本文所综述的这些系统的优点包括生产成本低、使用简便,以及检测方法具有视觉上的颜色变化。这些优点对于重金属离子检测而言是非常积极的进展,尤其是在禁止进行复杂实验室研究的地区。

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