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结核菌素反应阴性的活动性进展期肺结核

[Active-evolutive pulmonary tuberculosis with negative tuberculin reaction].

作者信息

Moisescu V, Nicoară O, Rusu L, Popescu M

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1977 Jan-Mar;26(1):9-17.

PMID:191895
Abstract

In a lot of 452 patients with various forms of tuberculosis, in various locations, the authors have investigated the efficiency of tests currently employed in detecting tuberculin sensitivity (intradermoreaction to PPD, the test to sensitines and the Ustvedt test), in relation with several immunologic tests performed in vitro (index of lymphoblastogenesis to PPD and/or phytohaemagglutinin, leucocyte migration inhibition test, and the rosette test). It was noted that the two groups of investigations give similar results when tuberculin reactions are positive and intense. Under the conventionally admitted threshold of tuberculinic allergy the test of blastic transformation of lymphocytes, and especially the leucocyte migration inhibition tests are still positive and may be considered as a valuable means for measuring infra-tuberculinic allergy, as well as for the diagnosis of latent tuberculous infections.

摘要

在452例患有各种类型结核病、病变位于不同部位的患者中,作者研究了目前用于检测结核菌素敏感性的试验(对结核菌纯蛋白衍生物的皮内反应、对敏感素的试验和乌斯韦特试验)的有效性,并与几种体外进行的免疫试验(对结核菌纯蛋白衍生物和/或植物血凝素的淋巴细胞母细胞形成指数、白细胞游走抑制试验和玫瑰花结试验)进行了关联研究。结果发现,当结核菌素反应呈阳性且强烈时,两组研究结果相似。在传统认可的结核菌素过敏阈值以下,淋巴细胞的母细胞转化试验,尤其是白细胞游走抑制试验仍呈阳性,可被视为测量亚结核菌素过敏以及诊断潜伏性结核感染的有价值手段。

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1
[Active-evolutive pulmonary tuberculosis with negative tuberculin reaction].结核菌素反应阴性的活动性进展期肺结核
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1977 Jan-Mar;26(1):9-17.
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