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代谢综合征与重度抑郁症:共病情况及病理生理重叠

Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlap.

作者信息

McIntyre Roger S, Rasgon Natalie L, Kemp David E, Nguyen Ha T, Law Candy W Y, Taylor Valerie H, Woldeyohannes Hanna O, Alsuwaidan Mohammad T, Soczynska Joanna K, Kim Byungsu, Lourenco Maria T, Kahn Linda S, Goldstein Benjamin I

机构信息

Mood Disorders Psychopharmacology Unit, University Health Network, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada.

出版信息

Curr Diab Rep. 2009 Feb;9(1):51-9. doi: 10.1007/s11892-009-0010-0.

DOI:10.1007/s11892-009-0010-0
PMID:19192425
Abstract

The metabolic syndrome and its components are associated with depressive symptomatology. This article discusses the rate of co-occurrence and the points of pathophysiologic commonality between the metabolic syndrome and major depressive disorder.

摘要

代谢综合征及其组成部分与抑郁症状相关。本文讨论了代谢综合征与重度抑郁症同时出现的比率以及病理生理共性要点。

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本文引用的文献

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Metabolic syndrome in patients with bipolar disorder.双相情感障碍患者的代谢综合征
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2
Antipsychotic drug mechanisms: links between therapeutic effects, metabolic side effects and the insulin signaling pathway.抗精神病药物作用机制:治疗效果、代谢副作用与胰岛素信号通路之间的联系。
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Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder.双相情感障碍患者样本中糖尿病和代谢综合征的患病率。
Atypical depression is associated with metabolic syndrome: a systematic review.
非典型性抑郁症与代谢综合征相关:系统综述。
Actas Esp Psiquiatr. 2022 Nov;50(6):266-275. Epub 2022 Nov 1.
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High-fat diet induces depression-like phenotype via astrocyte-mediated hyperactivation of ventral hippocampal glutamatergic afferents to the nucleus accumbens.高脂饮食通过星形胶质细胞介导的腹侧海马谷氨酸能传入纤维对伏隔核的过度激活诱导抑郁样表型。
Mol Psychiatry. 2022 Nov;27(11):4372-4384. doi: 10.1038/s41380-022-01787-1. Epub 2022 Sep 30.
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Sex differences in autonomic responses to stress: implications for cardiometabolic physiology.应激自主反应的性别差异:对心脏代谢生理学的影响。
Am J Physiol Endocrinol Metab. 2022 Sep 1;323(3):E281-E289. doi: 10.1152/ajpendo.00058.2022. Epub 2022 Jul 6.
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A comparison of negative affect and disinhibited eating between children with and without parents with type 2 diabetes.比较 2 型糖尿病患儿及其父母无 2 型糖尿病患儿的负性情绪和不受抑制的进食行为。
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Horm Behav. 2021 Nov;136:105060. doi: 10.1016/j.yhbeh.2021.105060. Epub 2021 Sep 16.
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