Teixeira Paulo José Ribeiro, Rocha Fábio Lopes
Instituto de Previdência dos Servidores do Estado de Minas Gerais, Belo Horizonte, MG, Brazil.
Braz J Psychiatry. 2007 Dec;29(4):330-6. doi: 10.1590/s1516-44462007000400007.
Metabolic syndrome is a highly prevalent disorder among the general population. Studies show an even higher prevalence among psychiatric patients. The objective of this study is to assess the prevalence of metabolic syndrome among inpatients of a psychiatric ward of a general hospital in Brazil and correlate it with their respective psychiatric diagnoses and with the antipsychotics and mood stabilizers used.
170 inpatients (mean age: 45.6 years) were evaluated according to the National Cholesterol Education Program criteria for metabolic syndrome, with a modification of the criteria for blood pressure and fasting glucose.
The prevalence found was 29.4%, being higher in women (43.6% versus 20.8%, p = 0.002). The prevalence stratified by psychiatric diagnostic was 48.1% for depression, 38.3% for bipolar disorder, 31.8% for schizophrenia and schizoaffective disorder, 5.1% for alcoholism, and 23.1% for "other mental disorders". The prevalence for alcoholism was significantly lower than the prevalence rates associated with other diagnostic categories (p = 0.035). After using the multivariate analysis, female gender and use of lithium remained as factors associated with a diagnosis of metabolic syndrome.
The prevalence found was 29.4%. Gender (female) and use of lithium were factors significantly associated with the diagnosis of metabolic syndrome.
代谢综合征在普通人群中是一种高度流行的疾病。研究表明，其在精神科患者中的患病率更高。本研究的目的是评估巴西一家综合医院精神科病房住院患者中代谢综合征的患病率，并将其与各自的精神科诊断以及所使用的抗精神病药物和心境稳定剂相关联。
根据美国国家胆固醇教育计划代谢综合征标准，对170名住院患者（平均年龄：45.6岁）进行评估，并对血压和空腹血糖标准进行了修改。
发现患病率为29.4%，女性患病率更高（43.6%对20.8%，p = 0.002）。按精神科诊断分层的患病率为：抑郁症48.1%；双相情感障碍38.3%；精神分裂症和分裂情感性障碍31.8%；酒精中毒5.1%；“其他精神障碍”23.1%。酒精中毒的患病率显著低于与其他诊断类别相关的患病率（p = 0.035）。使用多变量分析后，女性性别和锂的使用仍然是与代谢综合征诊断相关的因素。
发现的患病率为29.4%。性别（女性）和锂的使用是与代谢综合征诊断显著相关的因素。
