Marcus Frank I, Zareba Wojciech
Sarver Heart Center, Tucson, AZ, USA.
J Electrocardiol. 2009 Mar-Apr;42(2):136.e1-5. doi: 10.1016/j.jelectrocard.2008.12.011. Epub 2009 Feb 4.
The electrocardiogram (ECG) provides important information to aid in the diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). The ECG changes may be explained by the pathophysiology of the disease. The proximity of the right ventricle (RV) to the anterior chest leads (V(1) to V(4)) explains why the characteristic ECG abnormalities are most prominent in those lends. The specific ECG abnormalities reflect the pathophysiology of the disease including T-wave inversion due to scarring of the free wall of the RV, prolonged S-wave duration due to slow depolarization of the terminal part of the QRS because the RV is the last part of the heart to undergo depolatization, and epsilon waves due to slow conduction in the RV. The extent of ECG abnormalities correlate with the degree of structural change in the RV.
心电图（ECG）为致心律失常性右室心肌病/发育异常（ARVC/D）的诊断提供重要信息。心电图变化可由该疾病的病理生理学来解释。右心室（RV）靠近前胸导联（V1至V4），这就解释了为什么特征性心电图异常在这些导联中最为显著。特定的心电图异常反映了该疾病的病理生理学，包括由于右室游离壁瘢痕形成导致的T波倒置、由于QRS波终末部分缓慢去极化（因为右室是心脏最后进行去极化的部分）导致的S波时限延长，以及由于右室内传导缓慢导致的epsilon波。心电图异常的程度与右室结构改变的程度相关。
