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常年性变应性鼻炎患者下鼻甲黏膜肥大细胞数量:一项光学显微镜研究

Mast cell numbers in the mucosa of the inferior turbinate in patients with perennial allergic rhinitis: a light microscopic study.

作者信息

Drake-Lee A B, Moriarty B, Smallman L A

机构信息

Department of Otolaryngology, Queen Elizabeth Hospital, Birmingham.

出版信息

J Laryngol Otol. 1991 Sep;105(9):736-8. doi: 10.1017/s0022215100117165.

DOI:10.1017/s0022215100117165
PMID:1919342
Abstract

The number of mast cells in the inferior turbinate from patients with perennial allergy due to house dust mite were compared with ten normal controls. Ten random high powered fields were counted in the epithelium and the submucosa in samples which had been divided into two and fixed either in aqueous formalin or Carnoy's fixative. The sections from each block were stained with either Azure A or Chloroacetate esterase technique. No statistical differences were found. The lack of increase in mast cell numbers was attributed to degranulation since numbers have been shown to be increased in perennial allergy when sections are examined ultrastructurally.

摘要

将因屋尘螨导致常年性过敏患者的下鼻甲中的肥大细胞数量与十名正常对照者进行了比较。在已分成两半并固定于水性福尔马林或卡诺伊固定液中的样本的上皮和黏膜下层中,计数了十个随机高倍视野。每个组织块的切片用天青A或氯乙酸酯酶技术染色。未发现统计学差异。肥大细胞数量未增加归因于脱颗粒,因为超微结构检查切片时已表明常年性过敏中肥大细胞数量会增加。

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