Berger G, Goldberg A, Ophir D
Department of Otolaryngology, Meir General Hospital, Kfar Saba, Israel.
Am J Rhinol. 1997 Jan-Feb;11(1):63-6. doi: 10.2500/105065897781446775.
The number of mast cells in the inferior turbinates of patients with perennial allergic rhinitis and perennial nonallergic rhinitis was compared with normal controls. Mast cell counts expressed as the mean number in 100 high-power fields, assessed after Carnoy's fixation and toluidine blue staining were 1.84 in normal controls (n = 11), 4.39 in patients with perennial allergic rhinitis (n = 13), and 4.00 in those with perennial nonallergic rhinitis (n = 26). Statistical analysis confirmed that the density of mast cells in allergic as well as in nonallergic patients was significantly higher than in normal controls, whereas no significant difference was found between the number of mast cells in allergic and nonallergic patients. It is concluded that the number of mast cells in the inferior turbinate mucosa of patients with perennial rhinitis is increased compared with normal controls, and the increased number is not necessarily allergy-dependent.
将常年性变应性鼻炎患者、常年性非变应性鼻炎患者下鼻甲中的肥大细胞数量与正常对照组进行比较。肥大细胞计数以100个高倍视野中的平均数表示，在经卡诺固定液固定和甲苯胺蓝染色后评估，正常对照组（n = 11）为1.84，常年性变应性鼻炎患者（n = 13）为4.39，常年性非变应性鼻炎患者（n = 26）为4.00。统计分析证实，变应性和非变应性患者中肥大细胞的密度均显著高于正常对照组，而变应性和非变应性患者之间的肥大细胞数量未发现显著差异。得出的结论是，与正常对照组相比，常年性鼻炎患者下鼻甲黏膜中的肥大细胞数量增加，且增加的数量不一定依赖于过敏反应。
