Antoneeva I I, Petrov S B
Patol Fiziol Eksp Ter. 2008 Oct-Dec(4):6-7.
Immunohistochemical investigation of intraoperative biopsy specimens of ovarian cancer at different clinical stages of the disease has revealed enhanced proliferation of the index Ki-67 and PCNA expression as well as Mt p53 and Bcl-2 expression correlating with the disease stage. Cancer progression may be accompanied with a selection of p53+ cells with hyperexpression of Bcl-2 and high proliferative activity.