Yang Ping, Dumont Guy A, Ansermino J Mark
Department of Electrical and Computer Engineering, The University of British Columbia, 2332 Main Mall, Vancouver, BC, V6T 1Z4, Canada.
J Clin Monit Comput. 2009 Apr;23(2):75-83. doi: 10.1007/s10877-009-9163-2. Epub 2009 Feb 7.
Intraoperative heart rate is routinely measured independently from the ECG monitor, pulse oximeter, and the invasive blood pressure monitor if available. The presence of artifacts, in one or more of theses signals, especially sustained artifacts, represents a critical challenge for physiological monitoring. When temporal filters are used to suppress sustained artifacts, unwanted delays or signal distortion are often introduced. The aim of this study was to remove artifacts and derive accurate estimates for the heart rate signal by using measurement redundancy.
Heart rate measurements from multiple sensors and previous estimates that fall in a short moving window were treated as samples of the same heart rate. A hybrid median filter was used to align these samples into one ordinal series and to select the median as the fused estimate. This method can successfully remove artifacts that are sustained for shorter than half the length of the filter window, or artifacts that are sustained for a longer duration but presented in no more than half of the sensors.
The method was tested on both simulated and clinical cases. The performance of the hybrid median filter in the simulated study was compared with that of a two-step estimation process, comprising a threshold-controlled artifact-removal module and a Kalman filter. The estimation accuracy of the hybrid median filter is better than that of the Kalman filter in the presence of artifacts.
The hybrid median filter combines the structural and temporal information from two or more sensors and generates a robust estimate of heart rate without requiring strict assumptions about the signal's characteristics. This method is intuitive, computationally simple, and the performance can be easily adjusted. These considerable benefits make this method highly suitable for clinical use.
术中心率通常独立于心电图监测仪、脉搏血氧仪以及(如有)有创血压监测仪进行测量。这些信号中的一个或多个出现伪迹,尤其是持续性伪迹,对生理监测构成了严峻挑战。当使用时间滤波器抑制持续性伪迹时,常常会引入不必要的延迟或信号失真。本研究的目的是通过利用测量冗余来去除伪迹并得出心率信号的准确估计值。
将来自多个传感器的心率测量值以及落在短移动窗口内的先前估计值视为同一心率的样本。使用混合中值滤波器将这些样本排列成一个有序序列,并选择中值作为融合估计值。该方法可以成功去除持续时间短于滤波器窗口长度一半的伪迹,或者持续时间较长但在不超过一半的传感器中出现的伪迹。
该方法在模拟和临床病例中均进行了测试。在模拟研究中,将混合中值滤波器的性能与包括阈值控制伪迹去除模块和卡尔曼滤波器的两步估计过程的性能进行了比较。在存在伪迹的情况下,混合中值滤波器的估计精度优于卡尔曼滤波器。
混合中值滤波器结合了来自两个或更多传感器的结构和时间信息,并在无需对信号特征做出严格假设的情况下生成可靠的心率估计值。该方法直观、计算简单,并且性能易于调整。这些显著优点使得该方法非常适合临床应用。