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单纯疱疹病毒引起的对称性脑干脑炎

Symmetrical brainstem encephalitis caused by herpes simplex virus.

作者信息

Miura Shiroh, Kurita Takashi, Noda Kazuhito, Ayabe Mitsuyoshi, Aizawa Hisamichi, Taniwaki Takayuki

机构信息

Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan.

出版信息

J Clin Neurosci. 2009 Apr;16(4):589-90. doi: 10.1016/j.jocn.2008.06.005. Epub 2009 Feb 6.

DOI:10.1016/j.jocn.2008.06.005
PMID:19201192
Abstract

We describe a 53-year-old man with herpes simplex virus (HSV) brainstem encephalitis diagnosed based by positive HSV immunoglobulin M antibodies from cerebrospinal fluid. The MRI findings of this case had three unique features. First, the lesions were symmetrical. Second, the lesions may have been associated with reactivation of HSV infection in the region of the trigeminal nerve. Third, diffusion-weighted and apparent diffusion coefficient (ADC) imaging, conducted for the first time on an HSV brainstem encephalitis case, suggested that the lesions were associated with vasogenic edema.

摘要

我们描述了一名53岁男性,其因脑脊液中单纯疱疹病毒(HSV)免疫球蛋白M抗体呈阳性而被诊断为HSV脑干脑炎。该病例的MRI表现有三个独特特征。第一,病变是对称的。第二,病变可能与三叉神经区域HSV感染的再激活有关。第三,首次对HSV脑干脑炎病例进行的扩散加权成像和表观扩散系数(ADC)成像表明,病变与血管源性水肿有关。

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Symmetrical brainstem encephalitis caused by herpes simplex virus.单纯疱疹病毒引起的对称性脑干脑炎
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